Low Molecular Weight Dextran Sulfate (ILB^®) Administration Restores Brain Energy Metabolism Following Severe Traumatic Brain Injury in the Rat

• Main Authors: Giacomo Lazzarino (Author), Angela Maria Amorini (Author), Nicholas M. Barnes (Author), Lars Bruce (Author), Alvaro Mordente (Author), Giuseppe Lazzarino (Author), Valentina Di Pietro (Author), Barbara Tavazzi (Author), Antonio Belli (Author), Ann Logan (Author)
• Format: Book
• Published: MDPI AG, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Traumatic brain injury (TBI) is the leading cause of death and disability in people less than 40 years of age in Western countries. Currently, there are no satisfying pharmacological treatments for TBI patients. In this study, we subjected rats to severe TBI (sTBI), testing the effects of a single s...