THE ROLE OF MITOCHONDRIAL CALCIUM OVERLOAD IN CYCLOSPORINE A-INDUCED GINGIVAL HYPERPLASIA

• Main Authors: Ancuţa Goriuc (Author), Bogdan Minea (Author), Foia Liliana (Author), Marcel Costuleanu (Author), Raluca Jipu (Author), Vasilica Toma (Author), Vlad Cristiana (Author), Ionuţ Luchian (Author), Ioana Mârţu (Author)
• Format: Bog
• Udgivet: Romanian Society of Oral Rehabilitation, 2017-10-01T00:00:00Z.
• Fag: article
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Aim of the study Apoptosis (programmed cell death) is a possible mechanism of cyclosporine A (CsA)-induced gingival hyperplasia. The purpose of this paper is to study the effect of ionomycin and ionophore A23187 on normal gingival fibroblasts and also on fibroblasts treated with CsA using flow cytom...