Rapid oral transmucosal delivery of zaleplon-lavender oil utilizing self-nanoemulsifying lyophilized tablets technology: development, optimization and pharmacokinetic evaluation

• Autores principales: Sarah A. Ali (Autor), Nabil A. Alhakamy (Autor), Khaled M. Hosny (Autor), Eman Alfayez (Autor), Deena M. Bukhary (Autor), Awaji Y. Safhi (Autor), Moutaz Y. Badr (Autor), Rayan Y. Mushtaq (Autor), Majed Alharbi (Autor), Bader Huwaimel (Autor), Mohammed Alissa (Autor), Sameer Alshehri (Autor), Ali H. Alamri (Autor), Taha Alqahtani (Autor)
• Formato: Libro
• Publicado: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Based on the administration convenience, transmucosal buccal drug delivery allows special strength points over peroral routes for systemic delivery. It could achieve local or systemic effect and boost drugs' bioavailability for agents with first pass metabolism. The current study aimed to manuf...