Combination of polymeric micelle formulation of TGFβ receptor inhibitors and paclitaxel produces consistent response across different mouse models of Triple‐negative breast cancer

• Main Authors: Natasha Vinod (Author), Duhyeong Hwang (Author), Sloane Christian Fussell (Author), Tyler Cannon Owens (Author), Olaoluwa Christopher Tofade (Author), Thad S. Benefield (Author), Sage Copling (Author), Jacob D. Ramsey (Author), Patrick D. Rädler (Author), Hannah M. Atkins (Author), Eric E. Livingston (Author), J. Ashley Ezzell (Author), Marina Sokolsky‐Papkov (Author), Hong Yuan (Author), Charles M. Perou (Author), Alexander V. Kabanov (Author)
• Format: Book
• Published: Wiley, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Triple‐negative breast cancer (TNBC) is notoriously difficult to treat due to the lack of targetable receptors and sometimes poor response to chemotherapy. The transforming growth factor beta (TGFβ) family of proteins and their receptors (TGFRs) are highly expressed in TNBC and implicated i...