TLR3 activation by Clonorchis sinensis infection alleviates the fluke-induced liver fibrosis.

• Main Authors: Yuru Wang (Author), Pengtao Gong (Author), Xuancheng Zhang (Author), Xiaocen Wang (Author), Xu Zhang (Author), Nan Zhang (Author), Yanhui Yu (Author), Yeting Ma (Author), Haoyang Zhang (Author), Xichen Zhang (Author), Xin Li (Author), Jianhua Li (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Clonorchis sinensis is a zoonotic parasite associated with liver fibrosis and cholangiocarcinoma development. The role of toll-like receptors (TLRs) in C. sinensis infection has not yet been fully elucidated. Here, the TLR3 signaling pathway, cytokine expression and liver fibrosis were examined in C...