A New Computer Model for Evaluating the Selective Binding Affinity of Phenylalkylamines to T-Type Ca<sup>2+</sup> Channels
To establish a computer model for evaluating the binding affinity of phenylalkylamines (PAAs) to T-type Ca<sup>2+</sup> channels (TCCs), we created new homology models for both TCCs and a L-type calcium channel (LCC). We found that PAAs have a high affinity for domains I and IV of TCCs a...
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| Main Authors: | , |
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| Format: | Book |
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MDPI AG,
2021-02-01T00:00:00Z.
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