Formation, Signaling and Occurrence of Specialized Pro-Resolving Lipid Mediators-What is the Evidence so far?

• Main Authors: Nils Helge Schebb (Author), Hartmut Kühn (Author), Astrid S. Kahnt (Author), Katharina M. Rund (Author), Valerie B. O'Donnell (Author), Nicolas Flamand (Author), Marc Peters-Golden (Author), Per-Johan Jakobsson (Author), Karsten H. Weylandt (Author), Nadine Rohwer (Author), Robert C. Murphy (Author), Gerd Geisslinger (Author), Garret A. FitzGerald (Author), Julien Hanson (Author), Claes Dahlgren (Author), Mohamad Wessam Alnouri (Author), Stefan Offermanns (Author), Dieter Steinhilber (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Formation of specialized pro-resolving lipid mediators (SPMs) such as lipoxins or resolvins usually involves arachidonic acid 5-lipoxygenase (5-LO, ALOX5) and different types of arachidonic acid 12- and 15-lipoxygenating paralogues (15-LO1, ALOX15; 15-LO2, ALOX15B; 12-LO, ALOX12). Typically, SPMs ar...