Quality by design (QbD) approach to formulate in situ gelling system for nose to brain delivery of Fluoxetine hydrochloride: Ex-vivo and In-vivo study
ABSTRACT Objective: The purpose of the present study is to develop an ion sensitive in situ nasal gel of Fluoxetine hydrochloride for brain delivery. A 32 factorial design was used to investigate effect of independent variable on dependent variables. Methods: Formulations were evaluated for gelation...
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Facultad de Farmacia, Universidad de Granada.
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Internet
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A1234.567 |
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