A Bilayer Vaginal Tablet for the Localized Delivery of Disulfiram and 5-Fluorouracil to the Cervix

• Main Authors: Ismin Zainol Abidin (Author), Emanuele Rezoagli (Author), Bianca Simonassi-Paiva (Author), Gustavo Waltzer Fehrenbach (Author), Kevin Masterson (Author), Robert Pogue (Author), Zhi Cao (Author), Neil Rowan (Author), Emma J. Murphy (Author), Ian Major (Author)
• Format: Book
• Published: MDPI AG, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study was performed to develop an adjuvant therapy in the form of a self-administered vaginal tablet regimen for the localized delivery of chemotherapeutic drugs. This therapy will help to reduce relapse by eradicating cancerous cells in the margin of cervical tumors. The vaginal tablet is a ve...