Antisense Oligonucleotides against miR-21 Inhibit the Growth and Metastasis of Colorectal Carcinoma via the DUSP8 Pathway

• Main Authors: Tao Ding (Author), Panpan Cui (Author), Ya Zhou (Author), Chao Chen (Author), Juanjuan Zhao (Author), Hairong Wang (Author), Mengmeng Guo (Author), Zhixu He (Author), Lin Xu (Author)
• Format: Book
• Published: Elsevier, 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Accumulating research has documented that microRNA-21 (miR-21) plays an important role in the development of human colorectal carcinoma (CRC). Our recent work also showed that antisense oligonucleotides (ASOs) against miR-21 can impair the growth of CRC cells in vitro. However, the potential role of...