Streptococcus pneumoniae Impairs Maturation of Human Dendritic Cells and Consequent Activation of CD4+ T Cells via Pneumolysin

• Main Authors: Antje D. Paulikat (Author), Lea A. Tölken (Author), Lana H. Jachmann (Author), Gerhard Burchhardt (Author), Sven Hammerschmidt (Author), Nikolai Siemens (Author)
• Format: Book
• Published: Karger Publishers, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Influenza A Virus (IAV), Staphylococcus aureus (staphylococci), and Streptococcus pneumoniae (pneumococci) are leading viral and bacterial causes of pneumonia. Dendritic cells (DCs) are present in the lower respiratory tract. They are characterized by low expression of co-stimulatory molecules, incl...