Impact of neoadjuvant chemotherapy on somatic mutation status in high-grade serous ovarian carcinoma

• Main Authors: Zibi Marchocki (Author), Alicia Tone (Author), Carl Virtanen (Author), Richard de Borja (Author), Blaise Clarke (Author), Theodore Brown (Author), Taymaa May (Author)
• Format: Book
• Published: BMC, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Patients treated with neoadjuvant chemotherapy (NACT) for advanced high-grade serous ovarian carcinoma (HGSC) have a higher rate and shorter time to platinum-resistant recurrence compared to patients treated with primary cytoreductive surgery (PCS) and adjuvant chemotherapy. The...