A novel dendritic mesoporous silica based sustained hydrogen sulfide donor for the alleviation of adjuvant-induced inflammation in rats

• Main Authors: Yue Yu (Author), Zhou Wang (Author), Qinyan Yang (Author), Qian Ding (Author), Ran Wang (Author), Zhaoyi Li (Author), Yudong Fang (Author), Junyi Liao (Author), Wei Qi (Author), Keyuan Chen (Author), Meng Li (Author), Yi Zhun Zhu (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose S-propargyl-cysteine (SPRC), an excellent endogenous hydrogen sulfide (H2S) donor, could elevate H2S levels via the cystathionine γ-lyase (CSE)/H2S pathway both in vitro and in vivo. However, the immediate release of H2S in vivo and daily administration of SPRC potentially limited its clinic...