Angiogenesis Inhibitor Z24 Induces Endothelial Cell Apoptosis and Suppresses Tumor Growth and Metastasis

• Main Authors: Haiyan Lu (Author), Chen Lin (Author), Zhibing Zheng (Author), Song Li (Author), Shunxing Guo (Author), Xueyan Zhang (Author), Ming Fu (Author), Xiao Liang (Author), Min Wu (Author)
• Format: Book
• Published: Elsevier, 2005-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Z24, a small molecular compound with similar chemical structure to SU5416 designed and synthesized by our lab, has been proved to be an angiogenesis inhibitor. In this study, Z24 was shown to induce human umbilical venous endothelial cell (HUVEC) apoptosis confirmed by morphologic changes including...