Roles of rifampicin in drug-drug interactions: underlying molecular mechanisms involving the nuclear pregnane X receptor

• Asıl Yazarlar: Raymond Kenneth (Yazar), Chen Jiezhong (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: BMC, 2006-02-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

<p>Abstract</p> <p>Rifampicin, an important drug in the treatment of tuberculosis, is used extensively despite its broad effects on drug-drug interactions, creating serious problems. The clinical importance of such interactions includes autoinduction leading to suboptimal or failed...