CYP2C8*3 and *4 define CYP2C8 phenotype: An approach with the substrate cinitapride

• Main Authors: Diana María Campodónico (Author), Pablo Zubiaur (Author), Paula Soria‐Chacartegui (Author), Ana Casajús (Author), Gonzalo Villapalos‐García (Author), Marcos Navares‐Gómez (Author), Antía Gómez‐Fernández (Author), Raúl Parra‐Garcés (Author), Gina Mejía‐Abril (Author), Manuel Román (Author), Samuel Martín‐Vílchez (Author), Dolores Ochoa (Author), Francisco Abad‐Santos (Author)
• Format: Book
• Published: Wiley, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Cinitapride is a gastrointestinal prokinetic drug, prescribed for the treatment of functional dyspepsia, and as an adjuvant therapy for gastroesophageal reflux disease. In this study, we aimed to explore the impact of relevant variants in CYP3A4 and CYP2C8 and other pharmacogenes, along wit...