CYP2C8*3 and *4 define CYP2C8 phenotype: An approach with the substrate cinitapride

• প্রধান লেখক: Diana María Campodónico (লেখক), Pablo Zubiaur (লেখক), Paula Soria‐Chacartegui (লেখক), Ana Casajús (লেখক), Gonzalo Villapalos‐García (লেখক), Marcos Navares‐Gómez (লেখক), Antía Gómez‐Fernández (লেখক), Raúl Parra‐Garcés (লেখক), Gina Mejía‐Abril (লেখক), Manuel Román (লেখক), Samuel Martín‐Vílchez (লেখক), Dolores Ochoa (লেখক), Francisco Abad‐Santos (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Wiley, 2022-11-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Abstract Cinitapride is a gastrointestinal prokinetic drug, prescribed for the treatment of functional dyspepsia, and as an adjuvant therapy for gastroesophageal reflux disease. In this study, we aimed to explore the impact of relevant variants in CYP3A4 and CYP2C8 and other pharmacogenes, along wit...