Differential cellular immune responses against Orientia tsutsugamushi Karp and Gilliam strains following acute infection in mice.

• Main Authors: Joseph D Thiriot (Author), Yuejin Liang (Author), Casey Gonzales (Author), Jiaren Sun (Author), Xiaoying Yu (Author), Lynn Soong (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Scrub typhus is a leading cause of febrile illness in endemic countries due to infection with Orientia tsutsugamushi (Ot), a seriously understudied intracellular bacterium. Pulmonary involvement associated with vascular parasitism in patients is common and can develop into life threatening interstit...