Severe leptospirosis in tropical Australia: Optimising intensive care unit management to reduce mortality.

• Main Authors: Simon Smith (Author), Yu-Hsuan Liu (Author), Angus Carter (Author), Brendan J Kennedy (Author), Alexis Dermedgoglou (Author), Suzanne S Poulgrain (Author), Matthew P Paavola (Author), Tarryn L Minto (Author), Michael Luc (Author), Josh Hanson (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Severe leptospirosis can have a case-fatality rate of over 50%, even with intensive care unit (ICU) support. Multiple strategies-including protective ventilation and early renal replacement therapy (RRT)-have been recommended to improve outcomes. However, management gu...