Therapeutic Drug Monitoring and Individualized Medicine of Dasatinib: Focus on Clinical Pharmacokinetics and Pharmacodynamics

• Κύριοι συγγραφείς: Shiyu He (Συγγραφέας), Jialu Bian (Συγγραφέας), Qianhang Shao (Συγγραφέας), Ying Zhang (Συγγραφέας), Xu Hao (Συγγραφέας), Xingxian Luo (Συγγραφέας), Yufei Feng (Συγγραφέας), Lin Huang (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Frontiers Media S.A., 2021-12-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Dasatinib is an oral second-generation tyrosine kinase inhibitor known to be used widely in Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) and Ph+ acute lymphoblastic leukemia (ALL). Notably, although a high pharmacokinetic variability in patients and an increased risk of pleu...