Enhancement of innate immunity in gingival epithelial cells by vitamin D and HDAC inhibitors

• Main Authors: Erika L. Figgins (Author), Payal Arora (Author), Denny Gao (Author), Emily Porcelli (Author), Rabab Ahmed (Author), Carlo Amorin Daep (Author), Garrett Keele (Author), Lisa K. Ryan (Author), Gill Diamond (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

IntroductionThe human host defense peptide LL-37 is a component of the innate immune defense mechanisms of the oral cavity against colonization by microbes associated with periodontal disease. We have previously shown that the active form of vitamin D, 1,25(OH)2D3, can induce the expression of LL-37...