Tigecycline resistance may be associated with dysregulated response to stress in Mycobacterium abscessus

• Prif Awduron: Hien Fuh Ng (Awdur), Yun Fong Ngeow (Awdur), Sook Fan Yap (Awdur), Thaw Zin (Awdur), Joon Liang Tan (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Elsevier, 2020-01-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Previously, we characterized 7C, a laboratory-derived tigecycline-resistant mutant of Mycobacterium abscessus ATCC 19977, and found that the resistance was conferred by a mutation in MAB_3542c, which encodes an RshA-like protein. In M. tuberculosis, RshA is an anti-sigma factor that negatively regul...