Pre-clinical antigenicity studies of an innovative multivalent vaccine for human visceral leishmaniasis.

• Autors principals: Pedro Cecílio (Autor), Begoña Pérez-Cabezas (Autor), Laura Fernández (Autor), Javier Moreno (Autor), Eugenia Carrillo (Autor), José M Requena (Autor), Epifanio Fichera (Autor), Steven G Reed (Autor), Rhea N Coler (Autor), Shaden Kamhawi (Autor), Fabiano Oliveira (Autor), Jesus G Valenzuela (Autor), Luigi Gradoni (Autor), Reinhard Glueck (Autor), Gaurav Gupta (Autor), Anabela Cordeiro- (Autor)
• Format: Llibre
• Publicat: Public Library of Science (PLoS), 2017-11-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

The notion that previous infection by Leishmania spp. in endemic areas leads to robust anti-Leishmania immunity, supports vaccination as a potentially effective approach to prevent disease development. Nevertheless, to date there is no vaccine available for human leishmaniasis. We optimized and asse...