Abscisic Acid and Its Receptors LANCL1 and LANCL2 Control Cardiomyocyte Mitochondrial Function, Expression of Contractile, Cytoskeletal and Ion Channel Proteins and Cell Proliferation via ERRα

• Hoofdauteurs: Sonia Spinelli (Auteur), Lucrezia Guida (Auteur), Mario Passalacqua (Auteur), Mirko Magnone (Auteur), Vanessa Cossu (Auteur), Gianmario Sambuceti (Auteur), Cecilia Marini (Auteur), Laura Sturla (Auteur), Elena Zocchi (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2023-08-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

The cross-kingdom stress hormone abscisic acid (ABA) and its mammalian receptors LANCL1 and LANCL2 regulate the response of cardiomyocytes to hypoxia by activating NO generation. The overexpression of LANCL1/2 increases transcription, phosphorylation and the activity of eNOS and improves cell vitali...