Abscisic Acid and Its Receptors LANCL1 and LANCL2 Control Cardiomyocyte Mitochondrial Function, Expression of Contractile, Cytoskeletal and Ion Channel Proteins and Cell Proliferation via ERRα

• Главные авторы: Sonia Spinelli (Автор), Lucrezia Guida (Автор), Mario Passalacqua (Автор), Mirko Magnone (Автор), Vanessa Cossu (Автор), Gianmario Sambuceti (Автор), Cecilia Marini (Автор), Laura Sturla (Автор), Elena Zocchi (Автор)
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• Опубликовано: MDPI AG, 2023-08-01T00:00:00Z.
• Предметы: article
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The cross-kingdom stress hormone abscisic acid (ABA) and its mammalian receptors LANCL1 and LANCL2 regulate the response of cardiomyocytes to hypoxia by activating NO generation. The overexpression of LANCL1/2 increases transcription, phosphorylation and the activity of eNOS and improves cell vitali...