Abscisic Acid and Its Receptors LANCL1 and LANCL2 Control Cardiomyocyte Mitochondrial Function, Expression of Contractile, Cytoskeletal and Ion Channel Proteins and Cell Proliferation via ERRα

• मुख्य लेखकों: Sonia Spinelli (लेखक), Lucrezia Guida (लेखक), Mario Passalacqua (लेखक), Mirko Magnone (लेखक), Vanessa Cossu (लेखक), Gianmario Sambuceti (लेखक), Cecilia Marini (लेखक), Laura Sturla (लेखक), Elena Zocchi (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2023-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The cross-kingdom stress hormone abscisic acid (ABA) and its mammalian receptors LANCL1 and LANCL2 regulate the response of cardiomyocytes to hypoxia by activating NO generation. The overexpression of LANCL1/2 increases transcription, phosphorylation and the activity of eNOS and improves cell vitali...