Twin arginine translocation system in secretory expression of recombinant human growth hormone

• Main Authors: Mohammad Reza Bagherinejad (Author), Hamid Mir-Mohammad Sadeghi (Author), Daryoush Abedi (Author), C Perry Chou (Author), Fatemeh Moazen (Author), Mohammad Rabbani (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recombinant protein production in E. coli has several advantages over other expression systems. Misfolding, inclusion body formation, and lack of eukaryotic post translational modification are the most disadvantages of this system. Exporting of correctly folded proteins to the outside of reductive c...