A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors
<p>Abstract</p> <p>Background</p> <p>Hyperactivation of the Ras signaling pathway is a driver of many cancers, and RAS pathway activation can predict response to targeted therapies. Therefore, optimal methods for measuring Ras pathway activation are critical. The main f...
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Main Authors: | , , , , , , , , , , , , , , , , , |
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Format: | Book |
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BMC,
2010-06-01T00:00:00Z.
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Internet
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A1234.567 |
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