Interleukin-18 Increases TLR4 and Mannose Receptor Expression and Modulates Cytokine Production in Human Monocytes

• Автори: Luciane Alarcão Dias-Melicio (Автор), Reginaldo Keller Fernandes (Автор), Daniela Ramos Rodrigues (Автор), Marjorie Assis Golim (Автор), Angela Maria Victoriano Campos Soares (Автор)
• Формат: Книга
• Опубліковано: Hindawi Limited, 2015-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Interleukin-18 is a proinflammatory cytokine belonging to the interleukin-1 family of cytokines. This cytokine exerts many unique biological and immunological effects. To explore the role of IL-18 in inflammatory innate immune responses, we investigated its impact on expression of two toll-like rece...