Design, Development, and Evaluation of Treprostinil Embedded Adhesive Transdermal Patch

• Main Authors: Ibrahim Alissa (Author), Anroop B. Nair (Author), Bandar Aldhubiab (Author), Hiral Shah (Author), Jigar Shah (Author), Vivek Mewada (Author), Rashed M. Almuqbil (Author), Shery Jacob (Author)
• Format: Book
• Published: MDPI AG, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Clinical application of treprostinil in pulmonary arterial hypertension is hampered by adverse effects caused by its high dosing frequency. The objective of this investigation was to Formulate an adhesive-type transdermal patch of treprostinil and evaluate it both in vitro and in vivo. A 3<sup>...