Inhibition of poly(ADP-ribose)polymerase contributes to the reduction of oxidative stress in murine liver under the conditions of experimental endotoxemia
The aim of the work is to investigate the effect of the enzyme poly(ADP-ribose)polymerase 1 (PARP-1) inhibitor, 4-hydroxyquinazoline (4-HQN), on the state of the pro- and antioxidant system of murine liver, under the conditions of lipopolysaccharide (LPS) induced inflammation. Materials and methods....
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Zaporozhye State Medical University,
2019-12-01T00:00:00Z.
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