Association of obesity risk SNPs in <it>PCSK1 </it>with insulin sensitivity and proinsulin conversion
<p>Abstract</p> <p>Background</p> <p>Prohormone convertase 1 is involved in maturation of peptides. Rare mutations in gene <it>PCSK1</it>, encoding this enzyme, cause childhood obesity and abnormal glucose homeostasis with elevated proinsulin concentrations....
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2010-06-01T00:00:00Z.
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