Oral bioavailability enhancement of doxazosin mesylate: Nanosuspension versus self-nanoemulsifying drug delivery systems

• Main Authors: Al Zahraa G. Al Ashmawy (Author), Mohammad H. Alyami (Author), Noura G. Eissa (Author), Gehan F. Balata (Author), Hanan M. El Nahas (Author)
• Formato: Livro
• Publicado em: International Association of Physical Chemists (IAPC), 2023-11-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Background and purpose: Doxazosin mesylate (DOX) is an antihypertensive drug that possesses poor water solubility and, hence, poor release properties. Both nanosuspensions and self-nanoemulsifying drug delivery systems (SNEDDS) are becoming nanotechnology techniques for the enhancement of water solu...