Chronic social defeat stress-induced depression reduces BCG efficacy by promoting regulatory T-cell levels in mice

• Egile Nagusiak: Rohit Tyagi (Egilea), Xi Chen (Egilea), Atika Dhar (Egilea), Bing Yang (Egilea), Wei Zhou (Egilea), Aikebaier Reheman (Egilea), Yingying Lei (Egilea), Gang Cao (Egilea)
• Formatua: Liburua
• Argitaratua: BMC, 2023-12-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Abstract Despite the initial successes of the Bacillus Calmette-Guerin (BCG) vaccine in children, its efficacy against tuberculosis is highly variable. There is a lack of understanding about how mental conditions influence BCG vaccination. Here, we used the chronic social defeat stress (CSDS) model...