Tumor immune microenvironment and apoptotic markers in breast cancer patients carrying <I>BRCA1</I> gene mutations

• প্রধান লেখক: A. I. Stukan (লেখক), A. Yu. Goryainova (লেখক), O. Yu. Chukhray (লেখক), S. D. Maksimenko (লেখক), E. N. Imyanitov (লেখক), S. V. Sharov (লেখক), Z. K. Khachmamuk (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: ABV-press, 2022-09-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Background. It is suggested that defects in BRCA1 / 2 genes contribute to a high mutational load and high immunogenicity, which modulates immune microenvironment. At the same time, it was shown that BRCA1 / 2-associated breast cancer tumors do not belong to the category of immunoactive ones. These t...