Tumor immune microenvironment and apoptotic markers in breast cancer patients carrying <I>BRCA1</I> gene mutations

• Autores principales: A. I. Stukan (Autor), A. Yu. Goryainova (Autor), O. Yu. Chukhray (Autor), S. D. Maksimenko (Autor), E. N. Imyanitov (Autor), S. V. Sharov (Autor), Z. K. Khachmamuk (Autor)
• Formato: Libro
• Publicado: ABV-press, 2022-09-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Background. It is suggested that defects in BRCA1 / 2 genes contribute to a high mutational load and high immunogenicity, which modulates immune microenvironment. At the same time, it was shown that BRCA1 / 2-associated breast cancer tumors do not belong to the category of immunoactive ones. These t...