MicroRNA-Based Prophylaxis in a Mouse Model of Cirrhosis and Liver Cancer

• Main Authors: Elisa Callegari (Author), Marco Domenicali (Author), Ram Charan Shankaraiah (Author), Lucilla D'Abundo (Author), Paola Guerriero (Author), Ferdinando Giannone (Author), Maurizio Baldassarre (Author), Cristian Bassi (Author), Bahaeldin K. Elamin (Author), Barbara Zagatti (Author), Manuela Ferracin (Author), Francesca Fornari (Author), Giuseppe Altavilla (Author), Stella Blandamura (Author), Enrico Maria Silini (Author), Laura Gramantieri (Author), Silvia Sabbioni (Author), Massimo Negrini (Author)
• Format: Book
• Published: Elsevier, 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Most hepatocellular carcinomas (HCCs) arise in the context of chronic liver disease and/or cirrhosis. Thus, chemoprevention in individuals at risk represents an important but yet unproven approach. In this study, we investigated the ability of microRNA (miRNA)-based molecules to prevent liver cancer...