A graph-based algorithm for estimating clonal haplotypes of tumor sample from sequencing data

• Main Authors: Yixuan Wang (Author), Xuanping Zhang (Author), Shuai Ding (Author), Yu Geng (Author), Jianye Liu (Author), Zhongmeng Zhao (Author), Rong Zhang (Author), Xiao Xiao (Author), Jiayin Wang (Author)
• Format: Book
• Published: BMC, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Haplotype phasing is an important step in many bioinformatics workflows. In cancer genomics, it is suggested that reconstructing the clonal haplotypes of a tumor sample could facilitate a comprehensive understanding of its clonal architecture and further provide valuable referenc...