EZH2 is required for parathyroid and thymic development through differentiation of the third pharyngeal pouch endoderm

• Main Authors: Cinzia Caprio (Author), Gabriella Lania (Author), Marchesa Bilio (Author), Rosa Ferrentino (Author), Li Chen (Author), Antonio Baldini (Author)
• Format: Book
• Published: The Company of Biologists, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The Ezh2 gene encodes a histone methyltransferase of the polycomb repressive complex 2 that methylates histone H3 lysine 27. In this study, we investigated whether EZH2 has a role in the development of the pharyngeal apparatus and whether it regulates the expression of the Tbx1 gene, which encodes a...