Barriers in the Brain: Resolving Dendritic Spine Morphology and Compartmentalization

• Main Authors: Max eAdrian (Author), Remy eKusters (Author), Corette J Wierenga (Author), Cornelis eStorm (Author), Casper C Hoogenraad (Author), Lukas C Kapitein (Author)
• Format: Book
• Published: Frontiers Media S.A., 2014-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dendritic spines are micron-sized protrusions that harbor the majority of excitatory synapses in the central nervous system. The head of the spine is connected to the dendritic shaft by a 50-400 nm thin membrane tube, called the spine neck, which has been hypothesized to confine biochemical and elec...