Pharmacokinetics of DA-6886, A New 5-HT₄ Receptor Agonist, in Rats

• المؤلفون الرئيسيون: Dae Young Lee (مؤلف), Hee Eun Kang (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2022-03-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

DA-6886 is a novel serotonin (5-hydroxytrypamine [5-HT]) receptor 4 agonist for the potential treatment of constipation-predominant irritable bowel syndrome. The purpose of this study was to validate the quantitative assay of DA-6886 in rat plasma and to evaluate the pharmacokinetics and tissue dist...