Astrocytes underlie a faster-onset antidepressant effect of hypidone hydrochloride (YL-0919)

• Main Authors: Jin-Feng Li (Author), Wen-Yu Hu (Author), Hai-Xia Chang (Author), Jin-Hao Bao (Author), Xiang-Xi Kong (Author), Hui Ma (Author), Yun-Feng Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Major depression disorder (MDD) is a common and potentially life-threatening mental illness; however, data on its pathogenesis and effective therapeutic measures are lacking. Pathological changes in astrocytes play a pivotal role in MDD. While hypidone hydrochloride (YL-0919), an indep...