The importance of the toxicological analysis in newborns: clearing the case of a tetralogy of Fallot with a paradoxical reaction to 1-hydroxymidazolam

• Main Authors: Cristiano Ialongo (Author), Marco Marano (Author), Pierfrancesco Bertucci (Author), Luigi Tonino Marsella (Author), Andrea De Zorzi (Author), Sergio Bernardini (Author)
• Format: Book
• Published: Hygeia Press di Corridori Marinella, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Short half-life benzodiazepines like midazolam are used as premedication to relieve intra-partum pain, and are known to have no adverse effects to the newborn. However, such short-acting drugs are known to induce paradoxical reactions when their concentration is abnormally elevated respect to the ag...