SARS-CoV-2 Fusion Peptide Conjugated to a Tetravalent Dendrimer Selectively Inhibits Viral Infection

• Main Authors: Carla Zannella (Author), Annalisa Chianese (Author), Alessandra Monti (Author), Rosa Giugliano (Author), Maria Vittoria Morone (Author), Francesco Secci (Author), Giuseppina Sanna (Author), Aldo Manzin (Author), Anna De Filippis (Author), Nunzianna Doti (Author), Massimiliano Galdiero (Author)
• Format: Book
• Published: MDPI AG, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Fusion is a key event for enveloped viruses, through which viral and cell membranes come into close contact. This event is mediated by viral fusion proteins, which are divided into three structural and functional classes. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein...