Interplay between RNA-binding protein HuR and Nox4 as a novel therapeutic target in diabetic kidney disease
Objective: Glomerular injury is a prominent pathological feature of diabetic kidney disease (DKD). Constitutively active NADPH oxidase 4 (Nox4) is a major source of reactive oxygen species that mediates hyperglycemia-induced mesangial cell (MC) fibrotic injury. However, the mechanism that Nox4 utili...
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Main Authors: | Qian Shi (Author), Doug-Yoon Lee (Author), Denis Féliers (Author), Hanna E. Abboud (Author), Manzoor A. Bhat (Author), Yves Gorin (Author) |
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Format: | Book |
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Elsevier,
2020-06-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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