Organoruthenium(II) complexes of acetazolamide potently inhibit human carbonic anhydrase isoforms I, II, IX and XII

Two acetazolamide (AAZ) complexes with ruthenium(II) η6-p-cymene chloride were synthesised, characterised and tested for their inhibitory effects on several carbonic anhydrase (CA, EC 4.2.1.1) isoforms with pharmacological applications. Against human (h) isoform hCA I, the two complexes showed inhib...

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Main Authors: Sara Seršen (Author), Katja Traven (Author), Jakob Kljun (Author), Iztok Turel (Author), Claudiu T. Supuran (Author)
Format: Book
Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
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