Stability-indicating HPLC-DAD method for the simultaneous determination of fluoroquinolone in combination with a non-steroidal anti-inflammatory drug in pharmaceutical formulation

• Main Authors: Elaine de Oliveira Araujo (Author), Aline Marques Rosa (Author), Marcos Serrou do Amaral (Author), Rúbia Adrieli Sversut (Author), Adriano César de Morais Baroni (Author), Lincoln Carlos Silva de Oliveira (Author), Nájla Mohamad Kassab (Author)
• Format: Book
• Published: Universidade de São Paulo, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We developed and validated a stability-indicating assay method for the simultaneous determination of enrofloxacin and piroxicam in combination and in the presence of degradation products. Reverse-phase high-performance liquid chromatography analyses were carried out on a Vertisep C18 column and acet...