DYRK1A genetic variants are not linked to Alzheimer's disease in a Spanish case-control cohort

• Main Authors: Berciano José (Author), Valdivieso Fernando (Author), Sastre Isabel (Author), Frank Ana (Author), Pozueta Ana (Author), Mateo Ignacio (Author), Rodríguez-Rodríguez Eloy (Author), Sánchez-Juan Pascual (Author), Vázquez-Higuera José (Author), Bullido María J (Author), Combarros Onofre (Author)
• Format: Book
• Published: BMC, 2009-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>As dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) has been implicated in the abnormal hyperphosphorylation of tau in Alzheimer's disease (AD) brain, and the development of neurofibrillary tangles, we exam...