Potential Effects of Boldine on Oxidative Stress, Apoptosis, and Inflammatory Changes Induced by the Methylprednisolone Hepatotoxicity in Male Wistar Rats

• Váldodahkkit: Esraa Shuker (Dahkki), Manal Farhood (Dahkki), Ghofran Al-Qudaihi (Dahkki), Dalia Fouad (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: SAGE Publishing, 2022-03-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Background Synthetic glucocorticoid therapeutic agent methylprednisolone (MPL), when used for an extended period of time at high dose, promotes the development of reactive oxygen species (ROS)-induced liver toxicity. This study investigated the role of boldine, a natural antioxidant with anti-apopto...