Potential Effects of Boldine on Oxidative Stress, Apoptosis, and Inflammatory Changes Induced by the Methylprednisolone Hepatotoxicity in Male Wistar Rats

• Главные авторы: Esraa Shuker (Автор), Manal Farhood (Автор), Ghofran Al-Qudaihi (Автор), Dalia Fouad (Автор)
• Формат: ‌
• Опубликовано: SAGE Publishing, 2022-03-01T00:00:00Z.
• Предметы: article
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Background Synthetic glucocorticoid therapeutic agent methylprednisolone (MPL), when used for an extended period of time at high dose, promotes the development of reactive oxygen species (ROS)-induced liver toxicity. This study investigated the role of boldine, a natural antioxidant with anti-apopto...