Tigecycline Pharmacokinetic and Pharmacodynamic Profile in Patients with Chronic Obstructive Pulmonary Disease Exacerbation

• Main Authors: Maria Kipourou (Author), Olga Begou (Author), Katerina Manika (Author), Georgios Ismailos (Author), Paschalina Kontou (Author), Georgia Pitsiou (Author), Helen Gika (Author), Ioannis Kioumis (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: We aimed to evaluate the pharmacokinetic profile of tigecycline in plasma and its penetration to sputum in moderately ill patients with an infectious acute exacerbation of chronic obstructive pulmonary disease (COPD). Methods: Eleven patients hospitalized with acute respiratory failure d...