Therapeutic effects of curcumin liposomes and nanocrystals on inflammatory osteolysis: In vitro and in vivo comparative study

• Main Authors: Shan Huang (Author), Dongdong Xu (Author), Li Zhang (Author), Liang Hao (Author), Yujie Jia (Author), Xianlong Zhang (Author), Tao Cheng (Author), Jian Chen (Author)
• Format: Book
• Published: Elsevier, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Curcumin could inhibit periprosthetic osteolysis induced by wear debris and adherent endotoxin, which commonly cause prosthesis loosening and negatively influence the long-term survival of joint arthroplasty. However, its limited water solubility and poor stability pose challenges for its further cl...