Downregulation of the farnesoid X receptor promotes colorectal tumorigenesis by facilitating enterotoxigenic Bacteroides fragilis colonization

• Main Authors: Suhang Guo (Author), Yi Peng (Author), Yan Lou (Author), Lijuan Cao (Author), Junqing Liu (Author), Nengming Lin (Author), Sheng Cai (Author), Yu Kang (Author), Su Zeng (Author), Lushan Yu (Author)
• Format: Book
• Published: Elsevier, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Colorectal cancer (CRC) is the third most commonly diagnosed cancer and the second leading cause of cancer-related deaths in the world. The downregulation of farnesoid X receptor (FXR) is frequently founded in CRC patients. The current study found that the decreased expression of FXR in colorectal c...