Host Immune Responses Differ between M. africanum- and M. tuberculosis-Infected Patients following Standard Anti-tuberculosis Treatment.

• Main Authors: Leopold D Tientcheu (Author), Mariëlle C Haks (Author), Schadrac C Agbla (Author), Jayne S Sutherland (Author), Ifedayo M Adetifa (Author), Simon Donkor (Author), Edwin Quinten (Author), Mohammed Daramy (Author), Martin Antonio (Author), Beate Kampmann (Author), Tom H M Ottenhoff (Author), Hazel M Dockrell (Author), Martin O Ota (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Epidemiological differences exist between Mycobacterium africanum (Maf)- and Mycobacterium tuberculosis (Mtb)-infected patients, but to date, contributing host factors have not been characterised. We analysed clinical outcomes, as well as soluble markers and gene expression profiles in unstimulated,...