Design, physicochemical characterisation, and in vitro cytotoxicity of cisplatin-loaded PEGylated chitosan injectable nano / sub-micron crystals

• Main Authors: Muhammad H. Sultan (Author), Sivakumar S. Moni (Author), Saad S. Alqahtani (Author), Mohammed Ali Bakkari (Author), Abdulrahman Alshammari (Author), Yosif Almoshari (Author), Saeed Alshahrani (Author), Osama A. Madkhali (Author), Syam Mohan (Author)
• Format: Book
• Published: Elsevier, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The study aimed to develop cisplatin-loaded PEGylated chitosan nanoparticles. The optimal batch of cisplatin-loaded PEGylated chitosan nanoparticles had a + 49.9 mV zeta potential, PDI of 0.347, and % PDI of 58.9. Nanoparticle zeta size was 741.4 z. d.nm, the size in diameter was 866.7 ± 470.5 nm, a...